Gene Silencing by siRNA Nanoparticles Synthesized via Sonochemical Method
نویسندگان
چکیده
منابع مشابه
Effective gene silencing by multilayered siRNA-coated gold nanoparticles.
Small interfering RNA (siRNA) has been widely proposed to treat various diseases by silencing genes, but its delivery remains a challenge. A well controlled assembly approach is applied to prepare a protease-assisted nanodelivery system. Protease-degradable poly-L-lysine (PLL) and siRNA are fabricated onto gold nanoparticles (AuNPs), by alternating the charged polyelectrolytes. In this study, u...
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ژورنال
عنوان ژورنال: Journal of Nanomedicine & Nanotechnology
سال: 2014
ISSN: 2157-7439
DOI: 10.4172/2157-7439.1000204